Mechanically slowing down the rate at which teleporters can be used

[palpetinus]

Randomizing loot positions would be great, but it would be just an artificial bandaid to make it more tedious. Coupled with a cooldown, you'd have a waiting game, not very exciting.
I'd suggest no telesci cooldown and a randomized chance (~20%) that an interesting piece (locked crate, artifact,..) is instead a Space-Yeti, Wendigo or similar threat. Maybe instead of just putting it there, it could be an "Unstable Rift" that only pulls a hostile creature with telesci, so that going there physically isn't punished but telesci is a risk.