Major Handerspider sprites go under chairs

[Frank_Stein]

alt shift ctrl click the tile to get a list of everything there, and then attack the spider on that list

problem with that is that the menu takes one billion years to load and only does that tile, so if it moves, its useless

I agree that it's not a perfect solution, but it is possible to get to them. You've also got the option to get yourself some mouse traps and lay them out to trap the spider

 Dr Zoidcrab

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The trick is to move away from the thing they're hiding under and stop mindlessly trying to kill something in a place it's obviously at an advantage. If you're locked in the shuttle cockpit because you don't have access, maybe don't go in and get yourself trapped in the first place?